Shi Yuxue graduated from the Department of Architecture at Tongji University in Shanghai, specializing in Urban Planning and Management. She has held various positions, including Technician and Engineer at the Urban Construction Research Institute of the Architectural Science Research Institute of the National Construction Committee, Director and Deputy Chief Engineer at the Shanghai Urban Planning and Design Institute, Director of the Shanghai Urban Planning Administration Bureau, Deputy Secretary-General of the Shanghai Construction Committee, Deputy Director of the Science and Technology Committee of the Shanghai Construction Committee, and President of the Shanghai Human Settlements Research Association. In 2021, she donated 5 million RMB to the Tongji University Education Development Foundation.